Browsing TCC by Title
Now showing items 40-59 of 77
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Efeito do nocaute fígado-específico da Mitofusina 2 sobre o acúmulo de DNA mitocondrial NZB/BINJ em camundongos
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 19/11/2021)The mammalian mitochondrial DNA (mtDNA) shows a high mutation frequency, which can lead to severe diseases in humans. However, disease development relies on the mutation load, which is tissue specific. This is explained ... -
Efeitos da injeção intra-articular de plasma rico em plaquetas versus ácido hialurônico no processo inflamatório e características histopatológicas da cartilagem e sinóvia em animais com osteoartrite: uma revisão sistemática
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 27/03/2023)Osteoarthritis (OA) is a disease characterized by the wearing down of joint cartilage and changes in bone structures, causing pain and compromising patients' quality of life. One of the treatment options is intra-articular ... -
Enriquecimento ambiental na puberdade: o efeito no cuidado materno e na metilação de genes em fêmeas murinas
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 30/03/2023)Environmental enrichment (EE) is a procedure used to improve the living conditions of confined animals. It can impact the welfare of these animals by reducing stress, anxiety, and depressive-like behaviors, increasing the ... -
Ensaios celulares baseados em replicon de Chikungunya para identificação de antivirais
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 12/04/2022)Chikungunya virus (CHIKV), which causes Chikungunya fever, is a arbovirus transmitted by the Aedes aegypti mosquito, which periodically causes epidemics around the world and can become a serious public health problem. ... -
Estrutura da macrofauna edáfica em uma floresta ripária em recuperação na zona rural de São Carlos, SP
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 23/09/2024)The degradation of tropical forests, especially in riparian areas, compromises biodiversity and the ability of these ecosystems to provide essential services, such as nutrient cycling and water regulation. Forest restoration ... -
Estudo em diferentes concentrações de água residual de petróleo para o crescimento de Chlorella sorokiniana, Chlorella vulgaris, Desmodesmus spinosus e suas combinações
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 06/04/2023)Petroleum refining involves three steps: separation, conversion and reform. Within all these steps there is the use of water to obtain refined oil. The water that is used is discarded after refinement and when discarded ... -
Estudo sobre a ativação dos receptores canabinoides na função cardíaca de matrinxã, Brycon amazonicus: expressão de proteínas envolvidas no manejo do cálcio
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 18/06/2021)This study aimed to evaluate the effects of activation of CB1 and CB2 receptors on proteins involved in myocardial calcium handling of the tropical fish matrinxã, Brycon amazonicus. Three experimental groups were employed: ... -
Estudos in silico da formação de complexos de alguns fármacos relacionados com a obesidade e potenciais receptores-alvo
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 09/11/2021)Obesity is a global health problem in the most diverse geographic locations at all socioeconomic levels that affects several physiological functions and increases the risk of cardiovascular diseases, tumors, musculoskeletal ... -
Expressão gênica diferencial de abelhas Apis mellifera expostas a diferentes agrotóxicos: integração de informações por meio da construção de uma base de dados e identificação de assinaturas moleculares dos efeitos adversos
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 12/07/2024)Pesticides are utilized across diverse environments, including urban, industrial, agricultural, and livestock settings. Despite their effectiveness in pest control, pesticides exert detrimental effects on ecosystems and ... -
Expressão heteróloga e caracterização de mananases da família GH5
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 02/02/2024)Polysaccharides in plant cell walls are mainly composed of cellulose, a glucose homopolymer, and hemicellulose, a complex group of heterogeneous polymers and one of the largest sources of renewable organic matter, with ... -
Expressão, purificação e caracterização estrutural dos mutantes truncados da Hsp70-escort protein 1 humana
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 15/02/2024)The 70 kDa Heat shock protein (Hsp70 or HSPA in humans) is a highly conserved family of molecular chaperones that is expressed in various cellular compartments and is associated with several pathologies, including ... -
Genossensor eletroquímico contendo nanopartículas de ouro Para detecção sensível de sars-cov-2
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 18/04/2022)Since the emergence of the new coronavirus (SARS-CoV-2), more than 495 million people have been affected by this disease, leading to an estimated 6.17 million deaths. In this context, the World Health Organization (WHO) ... -
Identificação e expressão recombinante de um novo peptídeo de potencial antimicrobiano derivado da proteína de reconhecimento de Peptidoglicanos 3 humana
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 20/02/2024)During the 21st century, bacterial resistance to drugs has reached dangerous levels, necessitating the development of new therapeutic strategies to combat these pathogens. Among them, antimicrobial peptides (AMPs) emerge ... -
Impressão 3D para fins de reparo ósseo: uma revisão da literatura
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 15/02/2024)Bone fractures are a common condition that can affect people of all ages, often caused by trauma such as falls or accidents, or by diseases. The bone healing process is highly regulated, involving cells and growth factors. ... -
Imunoensaio de fluxo lateral para diagnóstico de tuberculose
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 09/11/2022)Tuberculosis is the leading cause of death among infectious diseases, according to the World Health Organization, and represents a major public health problem. About 1.4 million people died from tuberculosis worldwide in ... -
Imunoterapia clínica de células CAR-T usadas contra tumores – uma revisão sistemática
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 20/03/2023)Chimeric antigen receptor T cell therapy (CAR-T cell therapy) is a type of immunotherapy for cancer treatment that involves genetically modifying the patient's own T cells to express a specific CAR for a tumor antigen, ... -
Inibição da integrina αvβ3 em cultura celular 3D de células tumorais e endoteliais em ambiente hipóxico utilizando a desintegrina recombinante DisBa-01
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 11/11/2022)Breast cancer has a high global incidence, it was the most fatal type of cancer in 2020, When 66,280 new cases were estimated just in Brazil. The main problems associated with tumors are related to their metastatic behavior, ... -
Investigação de moléculas híbridas para o tratamento anticâncer
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 06/07/2022)Cancer is the attribution given to the uncontrolled growth and proliferation of abnormal cells capable of invading and destroying the adjacent tissue. According to the World Health Organization (WHO), the global growth in ... -
Investigando Chlorolobion braunii em escala laboratorial: uma abordagem fisiológica para o entendimento do efeito sinérgico de cobre e LEDs branco/azul/vermelho na síntese de biomoléculas
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 18/08/2023)Microalgae are photosynthetic microorganisms with extensive biodiversity and physiological plasticity, serving as primary producers in aquatic ecosystems. They play a crucial ecological role by contributing to the balance ... -
Isolamento e caracterização de bactérias endofíticas associadas a Paspalum vaginatum Swartz com potencial biotecnológico e agrícola para promoção de crescimento vegetal e biocontrole
(Universidade Federal de São Carlos, UFSCar, , Câmpus São Carlos, 14/09/2022)Paspalum species are important constituents in native pastures of tropical and subtropical regions of the Americas. Paspalum vaginatum is a grass native to coastal areas in Brazil and is widely used on golf courses in the ...