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Item type:Item, Sobre a luz e o silêncio : o plano de longa duração e a dinâmica do som no cinema de Carlos Reygadas(Universidade Federal de São Carlos, 2014-04-29) ;Reis, Hugo Leonardo Castilhos dos ;Miranda, Suzana Reck ;https://lattes.cnpq.br/8566012598222563https://lattes.cnpq.br/1644543442424911This work aims to discuss the cinema of Carlos Reygadas, with the focuses on the importance of sound and its dynamics within the long duration take, a procedure that strongly characterizes the style of this director. Initially, excerpts from films Japón (2002), Battle in Heaven (2005) and Silent Light (2007) were analyzed to highlight the formation of a stylistic corpus and a predominantly contemplative and sensory conception of cinema. Then we elected Silent Light as a conductive thread of a broader analysis in relation to the main crop. Therefore, we had as main references studies by David Bordwell (2008) on traditional directors of the plan-sequence, as well as the categories and theoretical assumptions of Michel Chion (1994, 2009) on the uses of sound in cinema.Item type:Item, Estudo de incorporação de whiskers de celulose em polietileno de baixa densidade (PEBD)(Universidade Federal de São Carlos, 2014-04-29) ;Teodoro, Kelcilene Bruna Ricardo ;Mattoso, Luiz Henrique Capparelli ;https://lattes.cnpq.br/5839043594908917https://lattes.cnpq.br/3203774759570089This research proposed the obtainment of cellulose whiskers from cotton fibers and their application in low density polyethylene matrix (LDPE). Cellulose whiskers was obtained from acid hydrolysis of cotton fibers and the reaction conditions were defined after study of different acid in hydrolysis reaction (under 45°C and 75 minutes, with HCl sample WCl, or H2SO4 sample WS, or mix of them in a proportion 1:1 sample WSCl). The main difference observed was the amount sulfate groups on whiskers surface due the use sulphuric acid in hydrolysis. These groups affected the properties of samples, increasing stability of whiskers in aqueous suspension, decreasing the tendency to agglomeration. However, due to these groups, cellulose is degraded at low temperatures. Once the nanocellulose (hydrophillic) needs to interact with LDPE (hydrophobic), two strategies was studied to compatibilize them: (i) production a nanocomposite based EVA poly (ethylene-covinyl acetate), a copolymer compatible with matrix and filler, since it have a polar phases (vinyl acetate monomer) and a nonpolar phase (ethylene monomer), and (ii) surface modification of cellulose whiskers by esterification reactions. Nanocomposites based EVA was prepared by polymeric solution where EVA was solubilized in mineral oil and then, the whiskers without surface modification (WS) was added, with aim dispersing them in LDPE. The characterizations this study showed that the solvent remained inside the structure polymeric, modifying their original properties and difficulting the interaction between cellulose and copolymer molecules. The sample WS and WCl was applied in esterification reactions with acetic acid, propionic acid and maleic anhydride. Whiskers extracted by hydrochloric acid and modified by maleic anhydride (WClMal), was produced by a simple methodology and presented thermal stability at processing temperatures. Thus, this sample was used to obtain nanocomposites with cellulose whiskers and LDPE, which was produced as films by extrusion process. Nanocomposites with LDPE and whiskers not modified (WCl) was produced to comparison. The characterizations of these materials confirmed the incorporation of whiskers in a polymeric matrix. The concentration that showed good dispersion and lower clusters was 1% (w/w) cellulose whiskers in LDPE matrix.Item type:Item, Mitigação de riscos e compartilhamento de informações na cadeia de suprimentos: efeitos na melhoria do desempenho de empresas agroindustriais(Universidade Federal de São Carlos, 2014-04-29) ;Tomas, Robson Nogueira ;Alcântara, Rosane Lúcia Chicarellihttps://lattes.cnpq.br/7053457212238829Empirical works have shown that risks in a supply chain can affect the efficiency of the flows of products, services and information in it, causing misalignment between activities, inefficiencies in operations and low firm performance. In this sense, we note that the inter organizational information sharing has been pointed out in several studies (e.g., LEE et al, 2012; GIUNIPERO and ELTANTAWY , 2004; BLACKHURST et al, 2011) as an element capable of mitigating several risks involved in the productive activities of a supply chain. This thesis fits into this perspective, more specifically, seeks to analyze the relationship between sharing information with suppliers and customers and the mitigation of risks in supply chains (i.e. disruptions, poor delivery performance, failure orders, poor demand forescast, and others). Moreover, it is expected to understand if this fact (risk mitigation) contribute to improving business performance. Thus, we performed an empirical study consists of three stages, namely: i) literature review, ii) conducting a test of hypotheses with data processing by means of the technique of Structural Equation Modeling, and iii) interviews for in-depth understanding of the hypotheses were confirmed. Overall, the results indicate that, for the studied sector, a share of effective and efficient information between the company and its key suppliers focus promotes the mitigation of supply disruptions and inefficiencies in distribution operations or fulfilling delivery times along the chain, even without an appropriate sharing of information on demand (by the closest ties of the final consumer) or occurring inconsistencies with regard to its prediction. Moreover, with respect to performance improvement from the risk mitigation, the results are conclusive and allow to state that the expected effect was confirmed, i.e., so smaller are the risks involving the activities of supply, production and distribution of a focal with its suppliers and customers, best will their performance results (operational , market and financial). As contribution of the study, besides to filling the gaps identified in the literature highlights the production of knowledge to data from the Brazilian situation, since this research focuses on a recent topic (risks mitigation in supply chains) in an industry specific, of agri-companies.Item type:Item, Crescimento inicial de cana-de-açúcar em latossolo com gradiente de saturação por alumínio e submetido à aplicação de vinhaça(Universidade Federal de São Carlos, 2014-04-30) ;Viglio, Larissa Marques ;Soares, Marcio Roberto ;https://lattes.cnpq.br/6337462438517339https://lattes.cnpq.br/4177909832142003An important strategy to round the problem of high acidity in soil and the toxicity aluminum (Al)consequent, limiting the full sugarcane development, it is based on the use of suitable varieties to these conditions. The application of vinasse is one practical routine in sugarcane cropping. The vinasse effect as fertilizer is well known, principally by reducing the use of potassium fertilizers. However, vinasse may attenuate the toxic effects of Al in soil by formation of complexes with organic acids of low molecular weight, improving further deepening of the root system sugarcane. The aim of this work was to study tolerance of three sugarcane varieties (RB855453, RB966928 e RB867515) to Al toxicity and to assess the influence of vinasse in the expansion of the root system in dystrophic Red Yellow Oxisol with gradient of Al saturation. The experiment was carried out in the greenhouse, on an entirely randomized design, in factorial arrangement, with three replicates. Sugarcane seedling were transplanted to PVC columns (0,8 m), each column consisted of four PVC rings. The PVC rings were filled with soil samples that offered an ascending gradient of Al saturation in depth (m%= 0,7; 7,9; 40,8; 62,6). The collection of the experiment was conducted 120 days after planting and it was determined the leaf chlorophyll index (ICF), stem diameter, plant height, dry weight of shoot and stratified root system dry matter . The largest amount of total root system dry matter in soil without the supply of vinasse was obtained from the RB867515 but with vinasse application this characteristic was presented by RB867515 and RB855453. The RB867515 was considered the most tolerant to Al, however the sugarcane varieties classification order based on tolerance index has varied according to vinasse application. The shoot biometric parameters, excepted by the stem diameter, were not considered indicators to differentiate the sugarcane genotypes from the phytotoxic Al in soil, as well as the ICF could not be adopted as an indicative parameter due by this stress. There were no significant alterations in soil chemical properties, especially in reducing the levels of Al and Al saturation index 90 days after vinasse application. The vinasse effect in increasing the percentage of roots at depth of 40 to 80 cm, has been verified only by RB966928.Item type:Item, Degradação eletroquímica do antibiótico ciprofloxacina utilizando eletrodos de diamante dopado com boro e dióxido de chumbo(Universidade Federal de São Carlos, 2014-04-30) ;Wächter, Naihara ;Rocha Filho, Romeu Cardozo ;https://lattes.cnpq.br/5200717413563550https://lattes.cnpq.br/8530485242303522Initial potentials for the oxygen evolution reaction (OER) of 2.23, 2.30, 2.36, and ~1.55 V vs. Ag/AgCl (3 mol L 1 KCl) were obtained by linear sweep voltammetry (LSV) in 0.1 mol L 1 Na2SO4 for the 2500, 100, and 500 ppm BDD, and the Ti-Pt/β-PbO2 electrodes, respectively. When LSW was used in the presence of 200 mg L 1 ciprofloxacin hydrochloride (Cl-cipro) in 0.1 mol L 1 Na2SO4, an oxidation peak was observed before the occurrence of the OER, for all the electrodes. Using the 100 ppm BDD electrode, LSV experiments were carried out for different Cl-cipro concentrations in 0.1 mol L 1 Na2SO4, which confirmed the nature of the oxidation peak at ~1.5 V vs. Ag/AgCl (3 mol L 1 KCl). With this electrode, LSW experiments were also carried out at different sweep values using the previously mentioned Clcipro solution, with results that indicated that the oxidation of the pharmaceutical drug is mainly a diffusion-controlled process. For the electrochemical degradation of ciprofloxacin (50 mg L 1 Cl-cipro) in 0.1 mol L 1 Na2SO4, using the BDD and Ti-Pt/β- PbO2 electrodes in filter-press type reactors, the effect of pH, flow rate, temperature, and current density was investigated. The degradation process was favored when the electrolyses were carried out at pH 10, which is related to the pKa values of the molecule. Yet the flow rate presented different effects; for the Ti-Pt/β-PbO2 electrode, the process efficiency was improved for a high value (6.5 L min 1), contrary to what was observed for the BDD electrodes (2,5 L min 1). The influence of temperature on the process was little marked, having a significant effect only for the 2500 ppm BDD electrode (best results at 10 °C). On the other hand, the electrodegradation of ciprofloxacin occurred faster at higher current densities, since greater amounts of the oxidizing agents are formed under these conditions. For the optimized condition, the 100 ppm BDD electrode presented the best performance in the oxidation and mineralization of the pharmaceutical drug. Under that condition and using the 100 ppm BDD, five ciprofloxacin degradation intermediates were identified (m/z 263, 306, 334, 348, and 362), which led to the proposal of an initial degradation route for its electrooxidation.Item type:Item, Uma linguagem de padrões semanticamente relacionados para o design de sistemas educacionais que permitam coautoria(Universidade Federal de São Carlos, 2014-05-03) ;Silva, Marcos Alexandre Rose ;Silva, Junia Coutinho Anacleto ;https://lattes.cnpq.br/6200743168568684https://lattes.cnpq.br/3381517748983487The adequacy of educational content considering student´s culture, knowledge and values allow them to identify the relationship between what they are learning and their reality and, consequently they feel more interested and engaged at education. In contrast, in informatics at education, designing educational systems to allow adequacy is a challenge because of a lack of techniques to support the design and the difficulty to identify what and how allow this adequacy by users, because many users of these systems, as educators and students, do not have knowledge of designing. In this context, it is presented here a formalization of the design pattern with successful solutions for recurrent problems on designing co-authorship systems analyzed and/or experienced by the researcher of this dissertation during design and evaluations of these systems at Advanced Interaction Laboratory (LIA). These patterns intend to support designing of educational systems that allow users, as co-authors, adequate these systems, inserting the content to be displayed at them. Each pattern describes specific problem and solution. In order to support indentifying how these patterns are organized to each other, semantic relations defined by Minsky are adopted to organize them based on humans´ intellectual structure. Validations with different participants´ profiles, e.g., with or without knowledge about concepts related to design, software engineering, human-computer interaction, co-authorship, etc., were done to formalize, refine and observe the comprehension and/or application of these patterns to design co-authorship system prototypes, as well as, different participants from mathematic or pedagogy areas and teachers to validate the use these of these prototypes. The results shown that the pattern language is comprehensible and it supports designing to define what and how to display on interface to allow and help users insert content.Item type:Item, Explorando caminhos de mínima informação em grafos para problemas de classificação supervisionada(Universidade Federal de São Carlos, 2014-05-05) ;Hiraga, Alan Kazuo ;Levada, Alexandre Luis Magalhães ;https://lattes.cnpq.br/3341441596395463https://lattes.cnpq.br/0420736258990939Classification is a very important step in pattern recognition, as it aims to categorize objects from a set of inherent features, through its labeling. This process can be supervised, when there is a sample set of labeled training classes, semi-supervised, when the number of labeled samples is limited or nearly inexistent, or unsupervised, where there are no labeled samples. This project proposes to explore minimum information paths in graphs for classification problems, through the definition of a supervised, non-parametric, graph-based classification method, by means of a contextual approach. This method proposes to construct a graph from a set of training samples, where the samples are represented by vertices and the edges are links between samples that belongs to a neighborhood system. From the graph construction, the method calculates the local observed Fisher information, a measurement based on the Potts model, for all vertices, identifying the amount of information that each sample has. Generally, different class vertices when connected by an edge, have a high information level. After that, it is necessary to weight the edges by means of a function that penalizes connecting vertices with high information. During this process, it is possible to identify and select high information vertices, which will be chosen to be prototype vertices, namely, the nodes that define the classes boundaries. After the definition, the method proposes that each prototype sample conquer the remaining samples by offering the shortest path in terms of information, so that when a sample is conquered it receives the label of the winning prototype, occurring the classification. To evaluate the proposed method, statistical methods to estimate the error rates, such as Hold-out, K-fold and Leave-One- Out Cross-Validation will be considered. The obtained results indicate that the method can be a viable alternative to the existing classification techniques.Item type:Item, Avaliação dos efeitos do resveratrol sobre o tecido ósseo de ratas ovariectomizadas(Universidade Federal de São Carlos, 2014-05-06) ;Fabricio, Victor ;Nonaka, Keico Okinohttps://lattes.cnpq.br/8413125497889474Resveratrol (trans 3,5,4 'trihydroxystilbene) is a polyphenol found in some plants and fruits. There are indications that it may be associated with the prevention of osteoporosis due to its action similar to a SERM (Selective Estrogen Receptor Modulators), a substance used to treat osteoporosis (among other diseases) in women whose use of hormone replacement therapy does not is indicated. However, more specific information about their effect in various quotas of bone tissue is still scarce. The aim of this study was to evaluate the ability of resveratrol to protect against bone changes characteristics of estrogen deficit in young adult ovariectomized rats. Were utilized 30 animals (Wistar rats) distributed into 3 groups: intact group (INT) with 10 intact animals, ovariectomized group (OVX) with 10 ovariectomized animals treated with a saline and dimethylsulfoxide (DMSO) solution, ovariectomized + resveratrol group (OVX + RES) with 10 ovariectomized animals treated with a resveratrol, saline and DMSO solution [0.7 mg/kg BW (body weight)], 7 times a week, for 12 weeks. Biometric, biophysical, biomechanical, microtomographical and radiographic density parameters were analyzed from bones with higher cortical (femur) and trabecular quota (vertebrae). The biomechanical properties of femurs were obtained by the three-point bending test and the lumbar vertebrae obtained by bone compression test. Lumbar vertebrae were used to perform the microtomographical analysis and radiographic density analysis. The ovariectomized rats gained more body weight and had lower bone density and radiographic density, and also showed reduction of microtomographical parameters when compared to the intact group. The biomechanical parameters of femurs did not change in neither group. The animals treated with resveratrol did not shown decrease in microtomographical parameters and bone density of the vertebrae as the untreated group. Therefore, the results suggest resveratrol as a potential protector of ovariectomy induced spoliation of bone tissues with greater trabecular quota.Item type:Item, Herbivoria de Bosmina freyi e suas relações ecológicas no Reservatório de Itupararanga - Votorantim/SP(Universidade Federal de São Carlos, 2014-05-07) ;Magalhães, Raphaella de Abreu ;Santos, André Cordeiro Alves dos ;https://lattes.cnpq.br/2131880667704281https://lattes.cnpq.br/7397911787609992Preliminary studies on reservoir Itupararanga indicate that the seasonal dynamics of plankton community is not being strongly controlled by bottom-up forces. Cianobactéria Cylindrospermopsis raciborskii and clorofícea Monoraphidium contortum are the dominant phytoplankton species in this reservoir. Bosmina freyi, recently described, is the dominant zooplankton in Itupararanga and there is no records of studies feeding habits of this specie. Therefore, the present study aims to assess the importance of the cladoceran Bosmina freyi as consumers of phytoplankton species: Monoraphidium contortum and Cylindrospermopsis raciborkii to better understand the ecological role of this organism in the planktonic food web in reservoir Itupararanga. M. contortum and three types of strain C.raciborskii, toxic strain (Cy.tox), strain with large filaments (Cy.grd) and strain with small filaments (Cy.peq) where ofered for Bosmina freyi. For each treatment, were calculated the density, cell volume, biovolume before and after incubation with B. freyi.Also calculated the ingestion and filtration rates. Qualitative models have also been made to describe and make predictions on the plankton community Itupararanga when there are changes in the population of Chaoborus sp. It was noted that B. freyi is able to efficiently ingest C.raciborskii including toxic strain, but presented difficulties in filter and ingest filaments of Cy.grd.Besides, B.freyi seems to be able to cut up filaments of C.raciborskii for ingestion. No food preference was observed by M.contortum. Qualitative models made in this study corroborate the hypothesis that seasonal variations in plankton reservoir Itupararanga may be being controlled by top-down forces due the presence of Chaoborus sp.Item type:Item, Efeitos antitumorais da naringenina complexada com cobre (II) e 2,2 -bipiridina em células de câncer de mama(Universidade Federal de São Carlos, 2014-05-07) ;Conceição Filho, Júlio César ;Cominetti, Márcia Reginahttps://lattes.cnpq.br/1613484530528398Cancer, is the name given to a set of more than 100 diseases that have in common the uncontrolled growth of cells that invade tissues and organs. It is occurs for several reasons, among them changes in DNA that may be caused by many factors such as oxidative stress, exposure to sunlight and smoking. Many efforts are being made in the search for treatments that may prolong a patient's life or even cure of the disease. In this quest, many chemotherapeutic compounds have been developed in an attempt to combat the different types of cancer. Among these various compounds were developed directly or indirectly from natural products derived from plants or bioactive compounds such as camptothecin, extracted from the bark of Camptotheca acuminata plant and taxol derivative of Taxus brevifolia. Flavonoids are a group of secondary metabolites, which belong to the class of polyphenols. They are found in several species of plants, especially in fruits, seeds and flowers. Many of them were described as having high antioxidant, anti-inflammatory, antiallergic, hepatoprotective and antitumor capacity. The main groups are derived from flavonoids are: flavanols, flavonols, isoflavones, anthocyanidins, flavonones, and flavones. The naringenin belongs to the group of flavonones commonly found in citrus fruits and has shown in previous studies to possess anti-tumor action. To make more effective the action of these compounds, many have been linked to metal complexes which increases the cytotoxicity of the same. One of the biggest challenges in the field of cancer research is to obtain a chemotherapeutic compound that is cytotoxic to tumor cells only and has fewer side effects compared to drugs currently used. Thus, the aim of this study was to evaluate and compare the cytotoxic effect of naringenin and naringenin complexed with copper and 2,2 '-bipyridine, in triple-negative breast cancer cell line, MDA-MB-231 and understand some of the mechanisms molecular action involved.Item type:Item, Avaliação do papel do receptor 5-HT2c da substância cinzenta periaquedutal sobre a antinocicepção induzida pelo predador (rato) em camundongos submetidos ao modelo de dor neuropática(Universidade Federal de São Carlos, 2014-05-08) ;Furuya-da-Cunha, Elke Mayumi ;Souza, Azair Liane Matos do Canto de ;https://lattes.cnpq.br/2352004564367849https://lattes.cnpq.br/9582420020561046Neuropathic pain is a type of chronic pain that can causes comorbidities such as generalized anxiety and depression, and, consequently, it produces considerable damage to the quality of life of affected people. Despite it being refractory to most conventional pharmacological treatments, studies evidence that serotonergic drugs, like antidepressants, are effective in treatment of this type of pain. Serotonin is a neurotransmitter with an important role in the modulation of nociceptive stimuli as well as the behaviors related to fear and anxiety. There is evidence that aversive situations, such as predator exposure may cause antinociception as a defensive reaction. Thus, several studies have demonstrated that fear or anxiety stimulus can cause antinociception and the serotonin (5-HT) produces this antinociceptive effect in structures of the central nervous system, such as the periaqueductal gray matter (PAG). In this sense, studies from our group demonstrate that activation of 5-HT2C receptors in PAG is involved in anxiolytic effects and in fear and anxiety-induced antinociception in mice exposed to the elevated plus maze. However, it is unknown what the role of PAG serotonergic receptors in the modulation of antinociception induced by exposure to predator (rat). Thus, the objective of this study was to evaluate the effect of activation of 5-HT2C receptors of PAG on the antinociception and defensive behaviors in mice submitted to sciatic nerve constriction. For this, Swiss-albino male mice were submitted to sciatic nerve constriction on the first day of the experiment and, seven days later, they received implantation of guide cannula in the PAG. Four days after stereotactic surgery, mice received intra-PAG injection of vehicle or mK212 and were exposed to the predator. The test consisted of two phases: a) habituation to the apparatus for 10 minutes for 3 consecutive days, which started the next day after stereotactic surgery; b) exposure to predators or neutral stimulus for 10 minutes. The analysis of variance (ANOVA) of three factors (condition x stimulation x treatment) showed that chronic constrition injured (CCI) mice exhibited increased of scratching behavior, that is indicative of chronic pain. The exposure of these animals to the predator (rat) produced antinociception in CCI mice and increased behaviors related to fear and anxiety such as time spent in protected area and total number of stretched attend posture (SAP) and decreased time of contact with the grid, when compared to mice exposed to neutral stimulus (toy rat). Treatment with mK212 intra-PAG (0.21 and 0.63 nmol) produced no significant change in antinociception and fear and anxiety assessed during exposure to rat. However, the mK212 0.21nmol dose treatment increased scratching behavior, indicating hyperalgesia in CCI mice exposed to toy rat. Thus, we suggest that 5-HT2C receptors of PAG appear to modulate differently this type of antinociception and fear and anxiety in mice. However, further studies should be conducted using more selective subtypes of serotonergic receptors and perhaps other models of nociception to enlarge and clarify the role of 5-HT2C receptors in the processes that modulate antinociception induced by aversive stimuli.Item type:Item, Desenvolvimento e reúso de frameworks com base nas características do domínio(Universidade Federal de São Carlos, 2014-05-08) ;Viana, Matheus Carvalho ;Penteado, Rosângela Aparecida Dellosso ;https://lattes.cnpq.br/4061946080136286https://lattes.cnpq.br/0839323666578855Frameworks are software artifacts that implement the basic functionality of a domain. Its reuse can improve the efficiency of development process and the quality of application code. However, frameworks are difficult to develop and reuse, since they require a complex structure to implement domain variability and be adaptable enough to be reused by different applications. Due to these difficulties, this research presents two approaches: 1) the From Features to Frameworks (F3) approach, in which the developer models the features of a domain and a pattern language helps in implementing a framework based on this model; and 2) the approach that uses a Domain-Specific Language (DSL) built from the identification and analysis of the domain features of a framework to facilitate the reuse of this framework. A tool, called From Features to Frameworks Tool (F3T), was also developed to support the use of these two approaches, providing editors for modeling domains and applications and automating the implementation of code of frameworks, DSLs and applications. In addition to facilitate the development and reuse of frameworks, experiments conducted during this project showed that these two approaches make these processes more efficient and allow the construction of frameworks and applications with less difficulty.Item type:Item, Basá busá: riqueza, cultura e política no alto rio Negro(Universidade Federal de São Carlos, 2014-05-09) ;Ferreira, Tatiana Amaral Sanches ;Andrello, Geraldo Luciano ;https://lattes.cnpq.br/5447074379881029https://lattes.cnpq.br/3263748217532898This work presents ethnographic research concerning recent initiatives of cultural revitalization in the Alto Rio Negro region, particularly those initiatives that have been taken by tukano speaking groups in the Uaupés river basin. Therefore, this study is a combination of short-term field work and bibliographic research. The case under analysis is that of the recent repatriation of a set of ceremonial ornaments (basá basá), which had been kept for decades at the Museu do Índio in the city of Manaus. Considering the impossibility of defining the communities to which these pieces had originally belonged, it was decided that the repatriated ornaments would become the collective property of the indigenous peoples of the Uaupés river basin, in custody of an indigenous organization pertaining to the multiethnic group of Iauaretê. This research showed that the ornaments are considered to be people with agency, in such a way that concerns relating to the appropriate uses and circulation of these objects arouse anxiety as to the misfortunes that such objects could bring about to those who used or manipulated them. However, some people from Iauarete affirmed that the ornaments could not only be tamed and revitalized, but also transmit important knowledge to those who used them.Item type:Item, Empatia em camundongos: avaliação do papel da amídala, insula e córtex cingulado anterior na nocicepção em camundongos expostos ao teste de contorções abdominais(Universidade Federal de São Carlos, 2014-05-09) ;Costa, Vinícius Pelarin do Nascimento ;Souza, Azair Liane Matos do Canto de ;https://lattes.cnpq.br/2352004564367849https://lattes.cnpq.br/0453820451521033Empathy can be defined as the capacity for perceive emotional signals from others. Among these signals, the ability to perceive pain has clear adaptive and evolutionary value. Pain can be defined as a subjective experience that includes sensorial, emotional and cognitive components. Evidence has emphasized the role of amygdala, anterior cingulate cortex (ACC) and insula in modulation of pain and empathy. Research indicates the capacity of rodents to express empathy to a conspecific in pain or suffering. Works from literature and finds from our laboratory demonstrated that living together with a cagemate is able to alter the nociceptive behavior in mice. However, there are no works evidencing if occur alterations in nociception by living together with a cagemate with chronic pain and which encephalic structures would be involved in this modulation. To overcome this, male Swiss-albino mice were housed in groups or in pairs. The role of amygdala, ACC and insula are accessed by non-selective inactivation with cobalt chloride (CoCl2). Mice housed in groups (Experiment 1), aging 6-8 weeks, underwent a stereotaxic surgery. 4 to 5 days after surgery, these animals received saline or CoCl2 microinjection, and, after 10 minutes, they were submitted to the writhing test during 5 minutes (acetic acid 0.6%, i.p., nociceptive stimulus). On the dyads (Experiment 2), animals lived together for 28 days since weaning. On the 14th day, one animal of each pair were submitted to a sciatic nerve constriction (SNC animal) or not (sham animal). On the 24th day, the cagemate underwent a stereotaxic surgery, and, on the 28th day, they were submitted to the writhing test after microinjection of saline or CoCl2, like the procedure described to Experiment 1. To Experiment 1 were utilized Student s t test to independent samples; to Experiment 2 were utilized two-way analysis of variance (ANOVA; living together x treatment). Duncan s multiple range tests were utilized as post hoc. A p value of 0.05 or less was required for significance in both experiments. In Experiment 1, inactivation of the amygdala increased the number of writhing, while inactivation of ACC and insula did not alter this measure, suggesting a distinct modulatory role of these structures on the sensorial compound of pain. Our results demonstrated that for the mice that lived in groups, while inactivation of the ACC and insula did not change writhing, inactivation of amygdala increased it, suggesting a distinct modulatory role of these structures on sensory component of pain in the writhing test. In Experiment 2, living together with a SNC-cagemate increased writhing on the pair, suggesting that this experience activates the circuitry of neural representation of pain on the observer mouse (state of priming ). Thus, when this animal experienced nociception, its response was exacerbated. In this condition, inactivation of insula and amygdala produces opposite results, i.e., decreased and increased in contortions in those animals that lived together with a SNC animal, respectively. ACC inactivation did not alter writhing behavior. In this sense, our results suggest a different modulatory role of these structures on cognitive, affective-emotional and sensorial components of pain, and on empathy for pain.Item type:Item, Identificação dos fatores que influenciam na escolha da rota pelos ciclistas: estudo de caso da cidade de São Carlos(Universidade Federal de São Carlos, 2014-05-12) ;Segadilha, Ana Beatriz Pereira ;Sanches, Suely da Penha ;https://lattes.cnpq.br/3857424839674606https://lattes.cnpq.br/1519870967702558This study reports on the information obtained by analyzing actual urban bicyclecommuter routes in São Carlos, using Global Positioning Systems (GPSs) for collecting the data and a Geographic Information System (GIS) for analyzing the data. The characteristics of the routes used by cyclists were compared with the characteristics of the shortest-path routes. The extra distance travelled was computed by the difference between these two lengths, and a multiple linear regression was created for explain the reason for this extra distance. The results showed that 70% of the trips were, at most, 15% longer than the shortest path, the average extra distance was 220 meters and the factors that have an influence was the street hierarchy and pavement quality.Item type:Item, Construção de mosaicos: uma análise por meio de tarefas exploratório-investigativas no 7°ano do ensino fundamental(Universidade Federal de São Carlos, 2014-05-15) ;Miranda, Sílvia Andrea Alexandre ;Oliveira, Paulo César ;https://lattes.cnpq.br/7516513469811353https://lattes.cnpq.br/1959724625898586The present study aimed to analyze how an education that prioritizes tasks of exploratory- investigative nature can contribute to the generation and/or mobilization of geometric concepts in the 7th grade students of elementary school. More specifically, the tasks contained in this dissertation fieldwork, contemplated the learning of geometrical concepts involved in the composition of mosaics with regular polygons. The investigation of a qualitative nature, in the form of case study occurred in a public school in the town of Pilar do Sul, the state of São Paulo, where the information was produced and collected between the first and the second semester of 2013. The technique of triangulation of data involved audio, video and photographs records, students written records and observation notes of the participant teacher - researcher. To describe and analyze the process of students learning we support in Ponte (2009 ) and his various studies on exploratory and investigative tasks, in Fischbein (1993 ) with the theory of figural concepts and Tall (1995); who studied the phases of human activity and mathematical reasoning. The survey results allowed to identify the students progress and difficulties to explore the tasks over time they were performed. With the experiences, the students began to develop clearer written records and used a mathematical language with greater mastery of mathematical terms, in particular the geometry. Furthermore, they demonstrated appropriating and/or expand figural concepts like angles, straight, regular polygons and mobilized such knowledge during the exploration of the properties and relations of these objects.Item type:Item, Efeito da prática de curta duração no alcance manual de lactentes pré-termo tardios: ensaio clínico controlado randomizado(Universidade Federal de São Carlos, 2014-05-15) ;Soares, Daniele de Almeida ;Tudella, Eloisa ;https://lattes.cnpq.br/3207258034860219https://lattes.cnpq.br/9965031852918633Objective: This thesis investigated the effect of a few minutes of reaching practice under different practice schedules on the reaching behavior of late preterm infants at the onset of goal-directed reaching. Method: This is a blind, three-arm parallel-group, randomized controlled trial. Thirty six late preterm infants (16,7 ± 2,3 weeks, chronological age) were allocated into groups that received reaching practice based on either a blocked schedule, a serial schedule, or no practice. The infants were assessed 3.3 ± 1.4 days after the onset of goal-directed reaching in three tests: pre-test (immediately before practice), post-test (immediately after practice), and retention test (24 h after post-test). Practice was applied between the pre- and the post-test (intrasession) and consisted of a 4 min. session of induced reaching using a toy in three activities guided by a physical therapist. The activities were elicited in separate blocks for the blocked practice group and in a serial order for the serial practice group. The control group stayed in the physical therapist s lap and was not stimulated to reach. During assessments, the infants were seated in a baby chair reclined 45º from the horizontal axis. A toy was presented at his/her midline within reaching distance for 2 min. The assessments were filmed and the images analyzed considering the following variables: number of reaches, proportions of proximal adjustments (uni and bimanual), distal adjustments (hand opening) and grasping outcome (reaches with and without grasping), and kinematic variables (straightness index, deceleration index, movement units, and velocity). Results: The major findings were increased amount of reaches from pre- to post-test for the serial practice group (p < 0.01). At the pre-test, the serial practice group performed unimanual reaches only; at the post-test, those infants increased the proportion of bimanual reaches compared to the pre-test (p = 0.05). There were no diferences between groups. Conclusions: Serial practice schedule may have required less perceptive and motor demands from the late preterm infants. The toyoriented experience, which stimulated the infants to perceive and act upon the toy successfully in a serial practice schedule, may have favored the infants perceptionaction coupling. This may have provided them with new oportunities to explore strategies to potentialize the transport of the hand towards the toy. Such stimuli were enough to lead to immediate, temporary adaptative changes.Item type:Item, Educação ambiental e o bibliotecário(Universidade Federal de São Carlos, 2014-05-15) ;Pinho, Fabio Assis ;Furnival, Ariadne Chloe Mary ;https://lattes.cnpq.br/1291482506649810https://lattes.cnpq.br/4220711855480007ABSTRACT This work has as its subject the potential contribution of the librarian to Environmental Education (EE), having as the main objective the possibility of identifying if the librarians of the network of libraries of UNESP are contributing and becoming efficient in the promotion and awareness of EE. The method used was explorative in character, by means of a case study with the librarians of the abovementioned network, using a questionnaire as the data collection instrument, and using a qualitative-quantitative and simple statistical analysis. The results demonstraed that the participation of the librarian as a informal educator in relation to EE is necessary, with possibilities of valuable and quality contribution in this work, and also that the library offers a space beyond the available resources for the viability of related projects in the area.Item type:Item, Desenvolvimento e caracterização de um banho não-cianetado para a eletrodeposição de ligas de Cu-Sn-Zn: caracterização dos eletrodepósitos(Universidade Federal de São Carlos, 2014-05-16) ;Carvalho, Marcos Fernandes de ;Carlos, Ivani Aparecida ;https://lattes.cnpq.br/1666217445807782https://lattes.cnpq.br/0922916090536806The electrodeposition of Cu-Sn-Zn ternary alloys onto AISI 1010 steel from an acid bath with EDTA or NTA salts was investigated, with various proportions of the metal ions in the baths. The concentration of these metals in the baths was determined by factorial design of mixtures with pseudocomponents. From potentiometric titration of these baths were determined regression equations, which led to studies of variance analysis and of surface response. These studies allowed to a pH of stabilization of the Cu-Sn-Zn electrodeposition baths. The Cu-Sn-Zn voltammetric profile showed five cathodic regions: c1, c1 , c2, c3 and c4 (depending on bath composition), and the conditional potentials for the Cu2+, Sn2+ and Zn2+ complexes indicated that these regions were associated, respectively, with reduction of [CuY]2- complex to Cu; [Sn(H2O)6]2+ complex to Sn; [SnY]2- complex to Sn; H2O to H2; and [ZnY]2- complex to Zn. In the presence of NTA, [Cu(NTA)2]4- and [SnNTA]-, [Sn(NTA)2]4-; H2O and [ZnNTA]- and [Zn(NTA)2]4-, respectively, in the regions c1, c2, c3 and c4. Cu-Sn-Zn electrodeposits produced at Ed 1.70 V with qd 3.0 C cm−2 were characterized by EDS, SEM, XRD and confocal optical microscopy (COM) analysis. EDS indicated that a transition potential exists wherein a transition from Cu-Sn binary alloy to Cu-Sn-Zn ternary alloy occurred and, also, that Cu-Sn-Zn co-deposition was normal, preferential or anomalous depending on the bath composition. Moreover, this analyze showed that Zn reduction was facilitated in the presence of NTA. SEM of electrodeposits showed that they were formed by globular and/or irregular crystallites, and, in general, by clusters of crystallites of different sizes dispersed on this layer, depending on the bath composition. COM analysis showed that electrodeposit produced from NTA was more roughness than with EDTA. XRD pattern indicated that the Cu-Sn-Zn electrodeposits, depending on the composition of the baths, presented low crystallinity or crystalline structure with mixture of SnO, η- Cu6Sn5 and Cu5Zn8 phases or pure Sn, η-Cu6Sn5 and Cu5Zn8 phases. Multivariate analysis allows extracting the maximum relevant chemical information from the data.Item type:Item, O primeiro Manoel de Barros e o aprendizado poético(Universidade Federal de São Carlos, 2014-05-16) ;Ferrari, Viviane de Cássia Duarte ;Marques, Wilton José ;https://lattes.cnpq.br/5763590592946918https://lattes.cnpq.br/6835842015001036The problem articulated in this work is to understand how the mato-grossense poet Manoel de Barros has been produced a modern poetry since the start of his career, when he had published the books Poemas concebidos sem pecado (1937) e Face imóvel (1942). To identify such a question, it will support, first in an overview of the barreano themes and stile, following, it will be done interpretative analysis of some poems from both books, in order to see if the modern aspects presented as marks on his poetry have already appeared since the beginning of his writings and if changes occurred in these traits throughout his literary creations. Thus, this research will verify the guiding-up elements of his first poetry, in order to establish relations between his initial poetic project and the rest of his works. This interpretative and comparative approach will contribute to the understanding and affinities of his unconventional lyrical. As it was seen here, both the recurrence of certain themes and some peculiarities of barreano style, it can show various signs of modernity which, in turn, helped to single out his poetics.