EnzyView: software para análise de reatores enzimáticos

Abstract

An important step while studying reactions catalyzed by enzymes is analyzing the behavior of bioreactors, considering different kinetics models and the order of magnitude of the parameters. Process simulations are one of the tools utilized for such porpoise, although the available softwares are paid and/or requires the user to have some specified knowledge to run simulations. The purpose of this project is to develop a simple free software able to simplify analyzes of enzymatic reactors by enabling the visualization of their behaviors. The software (EnzyView) was developed with a graphical user interface in XAML and logic in C#, using Windows Presentation Foundation. A total of 8 common Kinects models are available (Michaelis-Menten without inhibition, competitive, non-competitive, uncompetitive, partially competitive, partially noncompetitive, substrate inhibition, and enzyme deactivation), and 3 operational modes (Batch, CSTR, and CSTRs in series). Together they allow 28 different simulations, and the results are presented in graphical form, aiming to make it easier to understand reactional behavior. A tool (slider) enables quick value change in one of the simulation parameters is available, allowing simple analyses of its effects on the simulation model. With these functionalities, EnzyView can make study, teaching, and comprehension about enzymatic reactions easier, without a cost, and in a user-friendly way.